Cell-Box Bioproducts (Hong Kong) Trading Development Co., Ltd. (referred to as CB Company) was registered and established in Hong Kong in 2015. Initially focusing on international trade, the company has established technical exchanges and close collaborations with multiple manufacturers of bovine serum and cell culture reagents in the United States, Australia, and New Zealand. It provides high-quality products and services to scientific research users and distributors both domestically and internationally.

In December 2018, CB Company officially invested in and established a factory in mainland China, founding Changsha Cell-Box Biotechnology Co., Ltd. The production base is located in the Hunan Provincial (National-level) University Science and Technology Industrial Park, known for its beautiful environment and fresh air. The facility includes 100, 000-class, 10, 000-class, and 100-class production clean areas (with purification efficiency far superior to the commonly designed 100-class clean sheds in the domestic industry). It is also equipped with supporting purification facilities such as a secondary reverse osmosis water treatment system, an online steam sterilization system, and an air purification system with dual ozone and ultraviolet sterilization. Material feeding and filling are both completed within the 100-class production clean area. The production management system and product quality control standards are strictly operated in accordance with the international standards of the European Pharmacopoeia (EP), the United States Pharmacopoeia (USP), and the Chinese Pharmacopoeia (CHP).